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RO5263397 is often a TAAR1 precise agonist with oral action that has been Employed in antidepressant reports. It has also been uncovered to act as an inhibitor from the enzyme cyclooxygenase-two (COX-2), which is involved with the synthesis of prostaglandins.UCP. AAC-perpetrated mitochondrial H+ conductance is not really shown for clarity and on ac